Kratom Side Effects
Kratom is often described as producing simultaneous, contradictory effects. Users report both an opiate-like sedation and coca-like stimulation. The stimulating effects tend to predominate at low dose levels, which may cause alertness, energy, and mild euphoria. Higher doses tend to be more tranquilizing, causing an opiate-like dreamy reverie. Excessive doses can cause severe nausea. Kratom is sometimes used as an opium substitute and has been found to suppress symptoms of opiate withdrawal. As with opium, it is known for causing constipation, and is sometimes used as a treatment for diarrhea.
When taken orally, kratom effects typically become noticeable in 15-20 minutes and clearly apparent in 30-60 minutes. Strong doses may have a more rapid and dramatic onset.
A moderate kratom dose can cause strong effects lasting 2-4 hours, though residual effects can last hours longer. Users sometimes experience an afterglow the next day.
Some visual effects are reported, including both open-eye and closed-eye effects, though they are considered fairly mild if they occur at all. Effects reported include wavering, shifting, and strobing in the visual field; some patterning with eyes closed; and increased closed-eye visualizations.
Kratom is not known to be toxic, but it can be quite unpleasant at high doses, causing nausea and vomiting. Regular use can lead to physical dependency. Kratom use can cause constipation similar to that caused by opiates. Chronic heavy use is reported to cause darkening of skin, insomnia, dry mouth, and anorexia.
Do not operate heavy machinery. Do not drive.
Care should be taken if combining with other sedatives (or stimulants).
Use extreme caution if combining with MAO inhibitors. Kratom could be dangerous to combine with an MAOI.
Addiction Potential :
There are reports of physical dependency after frequent, heavy kratom use. Individuals who use it regularly or in large doses may find it difficult to stop. Withdrawal
symptoms include irritability, yawning, diarrhea, runny nose, and pain in the joints or muscles.
Long Term Health Problems:
Long Term Health Problems Summary Needed.
Risk of Death:
We are not aware of any cases of severe poisoning or death resulting from its use. Animal studies have found even very large doses of mitragynine (920 mg/kg) to be non-lethal.